Regenerates methionine from homocysteine using vitamin B12 as cofactor.
| Genotype | Impact | What it means |
|---|---|---|
| AA (Normal) | Normal | Normal methionine synthase activity and homocysteine metabolism. |
| AG (Carrier) | Low impact | Slightly altered homocysteine metabolism. B12 and folate important. |
| GG (Variant) | Moderate | May have elevated homocysteine levels. Ensure adequate B12 and folate intake. |
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