Nutrigenomics · PDF report

What your genes change about your diet, with the references to back it.

Upload the raw file from 23andMe, AncestryDNA, MyHeritage, FamilyTreeDNA or LivingDNA. We read over 40 nutrition-related genes and give you a PDF report in which every recommendation points to the gene involved and the study behind it.

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Folate
Vitamin D
Caffeine
Lactose
Lipids
Iron
Appetite

DNA double helix surrounded by foods: salmon, avocado, oats, banana, steak, egg and water

40+ nutrition genes PDF · 6 languages

Raw files accepted

23andMe
AncestryDNA
MyHeritage
FamilyTreeDNA
LivingDNA

Method

1
Upload the raw file

The .txt, .csv or .zip file exported from your provider, a few MB. A derived file (G25 coordinates, for example) is not enough.
2
Read the variants

Each genotype is read on the correct DNA strand. A genotype that cannot be read is left out rather than counted as “normal”.
3
Receive the report

A PDF in your language. For each recommendation: the gene, your genotype and the reference of the study.

Fig. 1From raw line to recommendation

01 File

# rsid      chromosome  position   genotype
rs1801133   1           11856378   AG

+ strand of the file → gene strand: AG = CT

02 Reading

MTHFR · C677T (rs1801133) · heterozygous, one copy of the variant

03 Effect

MTHFR enzyme activity reduced, about 60 to 70% of normal. It matters mostly when folate intake is low.

04 Report

Prefer folate-rich foods (leafy greens, legumes). Ask your doctor before taking any supplement.
PubMed · MTHFR C677T

A real variant reading, text taken from the report. The genotype shown is an example.

What the report reads

Extract: 7 areas out of 40+ genes

Area	Genes, examples	What the report draws from it
Folate and methylation	MTHFR · MTR · MTRR	Place of folate-rich foods and vitamin B12
Vitamin D	VDR · GC	Sunlight, diet, and when to test 25(OH)D
Caffeine	CYP1A2 · ADORA2A	How much coffee, and when to have the last cup
Lactose	MCM6 / LCT	Likely tolerance of dairy products
Lipids and heart	APOE · FADS1 · FADS2	Type of fats, omega-3 sources
Iron	HFE	Caution with iron supplements, ferritin testing
Appetite and weight	FTO · MC4R	Pointers for satiety and regular meals

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Pharmacogenomics: 11 genes, CPIC and PharmGKB guidelines
Gut and microbiome: secretor status, lactase, histamine
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Before you order: our reports read the raw DNA file from a test you have already taken (23andMe, AncestryDNA, MyHeritage, FamilyTreeDNA, LivingDNA). We do not sell test kits. Downloading your file is free: 23andMe · AncestryDNA · MyHeritage · other providers.

See a sample report (PDF)

What genetics does not tell you

A variant shifts a tendency. It makes no diagnosis and says nothing about your current state of health.

For several nutrients, a blood test says more than the gene: homocysteine, 25(OH)D, ferritin. The report says so whenever that is the case.

The report does not replace medical advice, especially during pregnancy or while on treatment.

References

[1]Ordovas JM, Ferguson LR, Tai ES, Mathers JC. Personalised nutrition and health. BMJ. 2018;361:k2173.
[2]Cornelis MC, El-Sohemy A, Kabagambe EK, Campos H. Coffee, CYP1A2 genotype, and risk of myocardial infarction. JAMA. 2006;295(10):1135-1141.
[3]Frayling TM, et al. A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science. 2007;316(5826):889-894.

What is nutrigenomics?