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HFE
Homeostatic Iron Regulator
Mineral Absorption Chr. 6 2 SNPs analyzed 5 food interactions

About this gene

Major regulator of iron absorption. Mutations cause hemochromatosis.

Analyzed variants (SNPs)

rs1799945 HFE H63D Population frequency: 14.0% Chr. 6 : 26,091,179
Genotype Impact What it means
CC (Normal) Normal Normal iron absorption
CG (Carrier) Low impact Mildly increased intestinal absorption, generally beneficial; monitor levels if relevant clinically.
GG (Variant) Moderate Increased iron absorption monitor levels
rs1800562 HFE C282Y Population frequency: 6.0% Chr. 6 : 26,093,141
Genotype Impact What it means
GG (Normal) Normal Normal iron regulation
GA (Carrier) Low impact Carrier slightly elevated iron absorption
AA (Variant) Very high Hemochromatosis risk monitor ferritin avoid iron supplements

Foods & nutrition for HFE

Use with caution

Use with caution
Beef Sirloin
High heme iron content
Use with caution
Beef Sirloin
High heme iron content

Foods to limit

Foods to limit
Beef Liver
Very high heme iron, avoid with HFE variants
Foods to limit
Beef Liver
Very high heme iron, avoid with HFE variants

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