Home / Gene Variants / APOE
APOE
Apolipoprotein E
Weight Management Chr. 19 2 SNPs analyzed 11 food interactions

About this gene

Major apoprotein involved in lipid transport and cardiovascular health

Gene function

Transports cholesterol and other fats in blood, affects heart disease risk

Analyzed variants (SNPs)

rs429358 APOE rs429358 E4 Population frequency: 15.0% Chr. 19 : 45,411,941
Genotype Impact What it means
TT (Normal) Normal Normal lipid metabolism. Standard dietary recommendations apply.
TC (Carrier) Moderate Altered lipid metabolism. Monitor cholesterol and focus on healthy fats.
CC (Variant) High impact Significantly altered lipid metabolism. Limit saturated fats, increase omega-3s.
📄 PubMed 2296103 🔗 Source study
rs7412 APOE rs7412 E2 Population frequency: 8.0% Chr. 19 : 45,412,079
Genotype Impact What it means
CC (Normal) Normal Normal lipid metabolism. Standard dietary recommendations apply.
CT (Carrier) Low impact Altered lipid metabolism. Monitor cholesterol and focus on healthy fats.
TT (Variant) Moderate Significantly altered lipid metabolism. Limit saturated fats, increase omega-3s.
📄 PubMed 2296103 🔗 Source study

Foods & nutrition for APOE

Beneficial foods

Beneficial foods
Wild Salmon
Omega-3 fatty acids reduce inflammation
Beneficial foods
Olive Oil
Heart-healthy monounsaturated fats
Beneficial foods
Olive Oil
Heart-healthy monounsaturated fats
Beneficial foods
Avocado
Healthy monounsaturated fats support lipid metabolism
Beneficial foods
Walnuts
Omega-3s support brain health for APOE4 carriers
Beneficial foods
Oats
Fiber helps manage cholesterol
Beneficial foods
Oats
Fiber helps manage cholesterol

Use with caution

Use with caution
Butter
High saturated fat content
Use with caution
Butter
High saturated fat content
Use with caution
Bacon
High in saturated fat, limit with APOE4
Use with caution
Bacon
High in saturated fat, limit with APOE4

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